Mirlabs
Dr Shailesh Kumar
Dr Shailesh Kumar
National Centre for Cell Science, Pune Maharashtra
PhD Student
Personal Web Site:
Main page: http://www.mirlabs.net/global/index.php?c=main&a=person&id=1156
Short Biography

Currently Working in the area of Interdisciplinary Research i.e. NLP in Biomedical Text mining for application of Information Technology in Biological Sciences. Applying Machine Intelligence for NER and RE which have wide application from classification of drugs, and other Biological Data Sets, Prediction, molecular modelling, high dimensional data analysis like Micro-array, and Next Generation Sequence Data analysis. 

Ph.D. Bioinformatics (2018), in the area of Bioinformatics  on title "Computational analysis of 5’ and 3’ UTR (Untranslated region) in human genome, to find impact of various genomic features to identify effective targets for Gene Silencing".  

M. Tech (IT) 2009 with Specialization in Bioinformatics from Indian Institute of Information Technology, Allahabad, Uttar Pradesh, India. 8.5 CGPI.

Graduate in Pharmaceutical Sciences in 2007 form Uttar Pradesh Technical University, Lucknow, Uttar Pradesh, India. 71.25%.

Qualified GATE in 2007 conducted by IIT-Delhi with 97.23 percentile. 

Qualified BINC 2013/ 2015 (Bioinformatics National Certification) with 17th/15th  Rank, conducted by Govt. of India.

Qualified CSIR NET 2019 with AIR 53 conducted by National Testing Agency, Government of India.


List of top 5 publications in the last 5 years

In-silico study of Betaine aldehyde dehydrogenase isozyme (BBD2) from Hordeum Vulgare: Homology modeling, Docking, and Molecular Dynamics simulation approach Hemani Sharma, Shailesh Kumar, Sumit Govil, and Divya Shrivastava, Research Journal of Biotechnology. 2020, 15(11),39-51.

Prediction of homologous genes by extracting Glycine max transcriptome using Hidden Markov Model”, Rakesh Sharma, Monika, Vandana Nunia, Shailesh Kumar, S. L. Kothari, Sumita Kachhwaha, Asian Journal of Pharmacy and Pharmacology, 2019; 5(6): 1117-1121.

The potential application of genome editing by using CRISPR/Cas9, and its engineered and ortholog variants for studying the transcription factors involved in the maintenance of phosphate homeostasis in model plants." Jyoti, Anupam, Sanket Kaushik, Vijay Kumar Srivastava, Manali Datta, Shailesh Kumar, Poli Yugandhar, Shanker L. Kothari, Vandna Rai, and Ajay Jain. In Seminars in Cell & Developmental Biology. Academic Press, 2019, S1084-9521(18)30112-5."

Targeting fatty acid synthase protein by molecular docking studies of naturally occurring Ganoderic acid analogues acting as anti-obesity molecule. Kaushal K Sharma, Shailesh Kumar, Brijendra Singh, Saurabh Bundela, Nisha Patro, Ishan K Patro, Prakash S Bisen. Research Journal of Biotechnology (Accepted).

Classification of 5’ and 3’ untranslated regions in human transcriptome by machine learning methods”. Shailesh Kumar, Sumit Govil, Vikram Kumar, Sumita Kachhawah, S L Kothari. Research Journal of Biotechnology, 2018, 13 (12), 47-53.

Identification of key miRNA biomarkers by miRNA-gene interactions network regulating breast cancer in human. Shailesh Kumar, Sumit Govil, Vikram Kumar, Sumita Kachhawah, S L Kothari. Asian Journal of Pharmacy and Pharmacology 2018; 4(5): 608-614.

Comparison of sequence with cluster based analysis for molecular properties and composition of glutathione peroxidase family proteins. Shailesh Kumar, Sumit Govil, Vikram Kumar. American Journal of Biotechnology and Bioinformatics, 2018; 2:6.

Micronutrient formulations for prevention of complications of pregnancy. R B Singh, Sanjay Mishra, Shailesh Kumar, Amit Mani Tiwari, Fabien De Meester, Ramesh K Goyal, Kumar Kartikey, Meenakshi Singh. Frontiers In Bioscience Scholar, 2018, 10, 175-184.

Biochemical isolation and characterization of Kojic acid derived from Aspergillus oryzae and Aspergillus flavus. Sudarshan Lakhawat, Vikram Kumar, Jignesh Chaudhary, Amrendra Nath Pathak, Shailesh Kumar. Research Journal of Biotechnology, 2018, 13 (6),30-35.

Computational prediction of mi-RNAs responsible for gene silencing in Helianthus tuberosusby using crossphylogeny approach with Arabidopsis thaliana. Sumit Govil, Shailesh Kumar. International Journal of Pharma and Bio Sciences, 2017; 8(4): (B)166-172

Metabolomic and biotechnological approaches to determine therapeutic potential of Withania somnifera (L.) Dunal: A Review. Tripathi, Niraj, Divya Shrivastava, Bilal Ahmad Mir, Shailesh Kumar, SumitGovil, Maryam Vahedi, and Prakash S. Bisen. Phytomedicine, 50, 127-136. (https://doi.org/10.1016/j.phymed.2017.08.020).

Morphological, biochemical and molecular characterization of Alternaria brassicicola and Alternaria brassicae: A comparative overview. Sanjay Mishra, Ruchi Singh, Shailesh Kumar, Sudheer Kumar. American Journal of Biochemistry and Molecular Biology, 7: 53-64. 10.3923/ajbmb.2017.53.64

A novel anticandidal compound containing sulfur from endophytic fungus Emericella sp. Shweta Mittal, Divya Shrivastava, Sumit Govil, Shailesh Kumar, Prakash Bisen. The Natural Products Journal, 2016, 6(3): 162-171.

Therapeutic applications of Crocus sativus L. (Saffron): A review. Maryam Vahedi, Sumit Govil, Shailesh Kumar, Divya Shrivastava, Roghaye Karimi, Prakash S Bisen. The Natural Products Journal, 2016, 6(3): 188-193.

Interaction pattern of Systemin with SR 160 receptor for activation of wound defensive gene. Mohan Kumar Yadav, Sumit Govil, Shailesh Kumar. International Journal of Pharmaceutical Technology and Biotechnology, 2015, 2(3):17-20

Computational studies on Ribavirin binding to RNA-dependent RNA polymerase, inducing Crimean-Congo hemorrhagic fever. Shailesh Kumar, Abhishek Tyagi, Sumit Govil and Sanjay Mishra (ISABB Journal of Biotechnology and Bioinformatics. ISSN: 2163-9758, Vol.2 (1), pp.1- 5, April 2012)

Computational 3D Structure Prediction, Evaluation and Analysis of Pyruvate Dehydrogenase an Effective Target for Filarial Infection by Brugia pahangi Using Homology Modeling Approach, Shailesh Kumar, Onkar Nath, Sumit Govil, A. N. Pathak. (International Journal of Pharmaceutical Sciences and Drug Research. ISSN: 0975-248X, 2014; 6(2): 120-123)

In-Silico Studies for Comparative Analysis of Glutathione Peroxides Isozymes in Homo Sapiens. Shailesh Kumar, Kirti Bhadhadhara, Sumit Govil, Nidhi Mathur, A. N. Pathak. (International Journal of Pharma and Biosciences. ISSN: 0975-6299, 2014 Oct; 5(4): (B) 352 - 363

A Review on Predictive Models and Classification of Inhibitors using Bioinformatics Approach. Mahima Tiwari, Sumit Govi, Shailesh Kumar, International Journal of Pharmaceutical Technology and Biotechnology, ISSN: 2394-2371. 2015; 2(1):26-32

Algorithms and databases: A key to solve genetic equation in Next Generation Sequencing”. Shailesh Kumar, Sumit Govil, SheemaSadana, A. N. Pathak. International Journal of advances in Pharmacy, Biology and Chemistry. 2014, 3(3), 709-716

List of top 5 academic activities during the last 5 years
Organised three day workshop on “Advanced Computer-Aided Drug Design and Computational Biology" held at Amity Institute of Biotechnology, Amity University Rajasthan, during 24-26 April 2019.
As member core committee for National conference on “Impact of climate change on air quality, Biodiversity and Agriculture”, at Amity University Rajasthan, Jaipur, India on 13-15 October 2016.
As Coordinator for Workshop in “Biomedical Instrumentation and Bioinformatics” held at Amity University Rajasthan Jaipur, India on 19-21 July 2016.
Worked as Organizing secretary in National Conference “Geographical Indications application filling and Awareness Program” at Amity University Rajasthan, Jaipur Held on 17-18 March, 2015.
Worked as Organizing secretary in Workshop and Hands on training on “Molecular Docking, Virtual Screening & Biologics Discovery” 18-20 February, 2015, Amity University Rajasthan Jaipur.
Worked as Co Convener in National conference on Advances in Mathematics, held at Amity University Rajasthan in collaboration with Bharat Ganita Parishad, Lucknow on 21-23 November 2014.
As Co-coordinator in National Conference Geographical Indications application filling and Awareness Program at Amity University Rajasthan, Jaipur Held on 24-25March, 2014.